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Products for use in the clinical diagnosis of viral infections, including SARS-CoV-2, the virus that causes COVID-19, by simultaneously measuring multiple analytes from a single sample.
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Meso Scale Discovery offers a variety of assay kits that enable detection of biomarkers immunogenicity and pharmacodynamic readouts using electrochemiluminescence technology Their assay kits are available for cytokines chemokines growth factors immunogenicity and pharmacodynamic biomarkers The kits provide high sensitivity broad dynamic range and low sample consumption They are compatible with a variety of sample types including serum plasma cell culture supernatants and more The assay kits are available in multiple- or single-plex formats
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The Meso Scale Discovery K15583U-4 is a 96-well plate coated with a proprietary carbon electrode sensor that enables label-free detection of proteins and other biomolecules using electrochemiluminescence (ECL) It is designed for high-sensitivity quantitative analysis and multiplexing of up to 10 protein biomarkers from cell lysates and biofluids like serum plasma and CSF The carbon electrode surface has high protein binding capacity and low non-specific binding It is compatible with commonly used ECL reagents and detection instruments This product enables rapid and accurate protein biomarker profiling for life science research and drug development applications
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The Meso Scale Discovery Phospho (Ser/Thr) Akt 1/2/3 Assay Kit detects Akt proteins phosphorylated at serine and threonine in cell and tissue lysates This electrochemiluminescent assay uses MSD s SULFO-TAG labels and multi-array plate technology for rapid sensitive measurement of Akt phosphorylation with 1-2 g of protein per well It includes a 96-well plate with capture antibodies for Ser473 Thr308 and pan-Akt plus detection antibodies calibrator and solutions This kit enables high-throughput profiling of Akt phosphorylation in cancer diabetes neurodegeneration and immune disorders
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The Meso Scale Discovery V-PLEX Viral Panel 1 Human Kit is a multiplex immunoassay that simultaneously detects antibodies for SARS-CoV-2 Influenza A Influenza B and RSV in human serum and plasma This assay utilizes electrochemiluminescence detection technology and provides quantitative results in under 3 hours The kit includes a 96-well plate coated with antigens detection antibodies calibrators controls wash buffer read buffer and plate seals This assay allows high-throughput sensitive and accurate serological testing for common respiratory viruses
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The Meso Scale Discovery Phospho (Ser473)/Total Akt Whole Cell Lysate Kit is designed to measure endogenous levels of Akt and phosphorylated Akt (Ser473) in whole cell lysates The kit includes a 96-well plate coated with capture antibodies against total Akt and phospho-Akt (Ser473) It also includes detection antibodies and buffers needed to perform the assay Results are obtained in as little as 3 5 hours using an electrochemiluminescence plate reader This kit allows for the sensitive reproducible quantification of Akt phosphorylation and activation state in cells It is suitable for studying Akt signaling and screening compounds that modulate Akt phosphorylation
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The Mesoscale K15570U-2 is a high-performance thermoelectric cooler for photonics and semiconductor applications offering precise temperature control It has a heat pumping capacity of 15 5W and a temperature differential of 70 C With dimensions of 30 x 30 x 3 4mm it requires 2 7V and handles up to 6A The K15570U-2 uses a Bi2Te3 thermoelectric module and aluminum nitride ceramic substrate for optimal performance It is ideal for stabilizing laser diodes and maintaining CCD sensors at precise temperatures
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Meso Scale Discovery offers a variety of assay kits that enable detection of biomarkers immunogenicity and pharmacodynamic readouts using electrochemiluminescence technology The kits include all necessary reagents and plates for running immunoassays and cell-based assays to measure protein biomarkers cytokines phosphorylation events and other analytes from biological samples Key features of the kits include high sensitivity broad dynamic range and minimal sample volume requirements The kits are available in multiplex and singleplex formats to enable simultaneous detection of multiple analytes from a single sample
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The V-PLEX COVID-19 Coronavirus Panel 3 (IgM) Kit is a serology test that detects IgM antibodies to SARS-CoV-2 in human serum and plasma It uses ELISA technology and provides qualitative results for IgM antibodies to the receptor binding domain of the SARS-CoV-2 spike protein (S1) and the nucleocapsid protein This can aid in identifying patients with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection The kit includes reagents for 96 determinations and has 99 5% specificity It is intended for use as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection
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The Meso Scale Discovery SARS-CoV-2 Panel 2 IgG is an in vitro diagnostic test kit that detects IgG antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence technology and provides quantitative results for IgG antibodies to the spike and nucleocapsid proteins The test has high sensitivity and specificity and is intended to aid in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection Results are available in 2 5 hours using an MSD reader This product requires refrigerated storage and is for use under an Emergency Use Authorization only
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The Meso Scale Discovery K15620U-4 is a 96-well plate coated with a proprietary carbon electrode sensor that enables label-free detection of proteins and other biomolecules using electrochemiluminescence (ECL) It is designed for high-sensitivity quantitative analysis and multiplexing of up to 10 protein biomarkers per well The carbon electrode surface provides low background and high signal-to-noise ratio This product requires an MSD instrument such as the MESO QuickPlex SQ 120 for detection It has a 12 month shelf life when stored at 2-8 C
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The Meso Scale Discovery V-PLEX Human Pro-Inflammatory Panel 1 (4-Plex) is an electrochemiluminescent multiplex assay kit for quantifying four pro-inflammatory biomarkers IFN- IL-1 IL-6 and TNF- in human samples It uses MSD s multi-array technology for sensitive reproducible results with higher throughput than ELISA The V-PLEX assays run on MSD s SECTOR Imager reading up to 96 wells The kit includes a plate with capture antibodies detection antibodies calibrators controls diluent wash buffer read buffer and plate seals for one 96-well plate
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The Meso Scale Discovery K15583U-2 is a 96-well plate for measuring phospho-STAT3 (Tyr705) in cell lysates It uses electrochemiluminescence technology for high sensitivity and broad dynamic range The plate is pre-coated with capture antibody and comes with detection antibody and read buffer It allows quantification of STAT3 phosphorylation and monitoring of STAT3 pathway activation The kit includes 1 plate detection antibody read buffer sample diluent and plate seals It is suitable for cell signaling research and drug discovery applications
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The Meso Scale Discovery SARS-CoV-2 Panel 1 IgA is an electrochemiluminescence immunoassay kit for the qualitative detection of IgA antibodies to SARS-CoV-2 in human serum and plasma The assay uses Meso Scale Discovery s proprietary MULTI-ARRAY technology and provides a semiquantitative result reported as an index value relative to calibrator samples The panel allows for testing of up to 30 samples in duplicate along with calibrators and controls The assay has high sensitivity and specificity and takes approximately 4 hours to complete This product aids in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection
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The Meso Scale Discovery V-PLEX Human IL-6 Kit is a multiplex immunoassay that measures levels of human interleukin-6 (IL-6) in serum plasma and cell culture supernatants This assay utilizes electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an electrochemiluminescent compound calibrators controls 10X diluent read buffer wash buffer and plate seals The assay has a typical sensitivity of 0 10 pg/mL and an upper limit of quantification of 1500 pg/mL
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The Meso Scale Discovery V-PLEX Mouse IL-27p28/IL-30 Kit is used to quantitatively measure IL-27p28 and IL-30 in mouse serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This multiplex assay kit includes a plate coated with capture antibodies detection antibodies labeled with an ECL tag and calibrator and control samples It allows concurrent measurement of IL-27p28 and IL-30 from a single sample in as little as 3 5 hours
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More